Объем | 50 мкг |
Синонимы | DIS3-like exonuclease 2 (hDIS3L2) (EC 3.1.13.-), DIS3L2, FAM6A |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q8IYB7 |
Иммуноген | Recombinant Human DIS3-like exonuclease 2 protein (201-400AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, IHC, Recommended dilution: IHC:1:20-1:200 |
Примечание | 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Области исследований | Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human ovarian tissue using CSB-PA818258LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human bladder cancer using CSB-PA818258LA01HU at dilution of 1:100
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