Объем | 50 мкл |
Синонимы | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q99704 |
Иммуноген | Fusion protein of human DOK1 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB,ELISA:1:2000-1:5000, WB:1:500-1:2000 |
Примечание | The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Gel: 8%SDS-PAGE,Lysate: 40 ?g,Lane 1-2: Human hepatocellsular carcinoma tissue, Jurkat cells,Primary antibody: CSB-PA040823(DOK1 Antibody) at dilution 1/450 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 20 seconds
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