Объем | 50 мкл |
Синонимы | Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (hDTX2) (RING finger protein 58) (RING-type E3 ubiquitin transferase DTX2), DTX2, KIAA1528 RNF58 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q86UW9 |
Иммуноген | Recombinant Human Probable E3 ubiquitin-protein ligase DTX2 protein (1-280AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
Примечание | Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Абревеатура | Probable E3 ubiquitin-protein ligase DTX2 |
Области исследований | Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: DTX2 antibody at 1µg/ml + HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 68, 63 kDa
Observed band size: 68, 92 kDa
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Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA803123ESR2HU at dilution of 1:100
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