EGFR (Ab-1092) AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Receptor tyrosine-protein kinase ErbB-1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P00533 | Иммуноген | Peptide sequence around aa. 1090~1094 (P-E-Y-I-N) derived from Human EGFR. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 | Примечание | Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia<br/><br/>Buerger C, et al. (2003) J Biol Chem, 278(39): 37610-21.<br/>Wang XQ, (2003) J Biol Chem, 278(49): 48770-8.<br/>Saito T, et al. (2004) Endocrinology, 145(9): 4232-43.<br/>Pao W, et al. (2004) Proc Natl Acad Sci U S A, 101(36): 13306-11.<br/>Mattila E, et al. (2005) Nat Cell Biol, 7(1): 78-85.<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Области исследований | Cancer,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HepG2, 293 and Hela cells using EGFR(Ab-1092) Antibody.
| Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using EGFR(Ab-1092) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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