| Объем | 100 мкл |
| Синонимы | EC 2.7.1.112, EC 2.7.10.1, EPB4, Ephrin type-B receptor 4 precursor, HTK |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P54760 |
| Иммуноген | Synthesized peptide derived from internal of human EPHB4. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.<br/><br/>Bennett B.D., J. Biol. Chem. 269:14211-14218(1994).<br/>Wilson M.D., Nucleic Acids Res. 29:1352-1365(2001).<br/>Zhang Y., Mol. Cell. Proteomics 4:1240-1250(2005). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Neuroscience,Cardiovascular,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells and Jurkat cells, using EPHB4 antibody.
 |
| | |
Наименование: EPHB4 Antibody.