FGFR1 (Ab-721) AntibodyСпецификацияОбъем | 100 мкл | Синонимы | KIT, CD117, SCFR, PBT, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P11362 | Иммуноген | Peptide sequence around aa.719~723 (N-E-Y-M-D) derived from Human c-Kit. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,WB:1:500-1:1000 | Примечание | This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)<br/><br/>Kimura W,et al.(2007)Hepatogastroenterology.54(80):2203-8.<br/>Naeem M,et al.(2002)Hum Pathol. 33(12):1182-7. <br/>Jankulovski N, et al.(2006)Prilozi. 27(2):59-70.<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cancer,Cardiovascular,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from A431 cells using c-Kit(Ab-721) Antibody and the same antibody preincubated with blocking peptide.
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