FOXO4 AntibodyСпецификацияОбъем | 50 мкл | Синонимы | Forkhead box protein O4, Fork head domain transcription factor AFX1, FOXO4, AFX, AFX1, MLLT7 | Тип антител | Recombinant Antibody | Species | Human | UniProt ID | P98177 | Иммуноген | A synthesized peptide derived from human FOXO4 | Видовая специфичность | Human | Применение | ELISA | Клональность | Monoclonal | Изотип | Rabbit IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Affinity-chromatography | Области исследований | Cell Biology | Аббревиатура | Forkhead box protein O4 | Примечание | Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity. | Ссылка на страницу на сайте производителя | ссылка | | |
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