Объем | 100 мкг |
Синонимы | GRB2-associated-binding protein 2 (GRB2-associated binder 2) (Growth factor receptor bound protein 2-associated protein 2) (pp100), GAB2, KIAA0571 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9UQC2 |
Иммуноген | Recombinant Human GRB2-associated-binding protein 2 protein (273-484AA) |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC, IF, Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Примечание | Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | GRB2-associated-binding protein 2 |
Области исследований | Neuroscience, Cancer, Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA892175LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA892175LA01HU at dilution of 1:100
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Immunofluorescent analysis of Hela cells using CSB-PA892175LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Western Blot
Positive WB detected in: Mouse brain tissue
All lanes: GAB2 antibody at 2.5µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 75, 70 kDa
Observed band size: 75 kDa
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