Объем | 100 мкл |
Синонимы | Glucokinase regulatory protein, Glucokinase regulator, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q14397 |
Иммуноген | Synthesized peptide derived from internal of human Glucokinase Regulator. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.<br/><br/>Warner J.P., Mamm. Genome 6:532-536(1995).<br/>Hayward B.E., Genomics 49:137-142(1998).<br/>Rieder M.J., Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from mouse heart cells and rat heart cells, using Glucokinase Regulator antibody.
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