Объем | 50 мкл |
Синонимы | GDNF family receptor alpha 2 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O00451 |
Иммуноген | Synthetic peptide of human GFRA2 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,ELISA:1:1000-1:5000, WB:1:200-1:1000 |
Примечание | Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Neuroscience |
Ссылка на страницу на сайте производителя | ссылка |
Gel: 10%SDS-PAGE, Lysate: 60 ?g, Lane: Human liver cancer tissue, Primary antibody: CSB-PA150222(GFRA2 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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