GRM6 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | EAA4, GLR6, MGC74427, bA487F5.1 (glutamate receptor, ionotropic | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | O15303 | | Иммуноген | Synthesized peptide derived from human GluR6. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity By similarity. Signaling stimulates TRPM1 channel activity and Ca2+ uptake. Required for normal vision.<br/><br/>Inga Everts, J. Neurosci., Feb 1999, 19: 916.<br/>Gregory D. Salinas, J. Biol. Chem., Dec 2006, 281: 40164 - 40173.<br/>Sheng Yan, J. Neurosci., Jan 2004, 24: 679.<br/>Xiao-Mei Liu, J. Biol. Chem., Jun 2006, 281: 17432 - 17445.<br/><br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR6 antibody.
 | Western blot analysis of extracts from mouse brain, using GluR6 antibody.
 | Western blot analysis of extracts from HepG2 cells (Lane 2), using mGluR6 antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: GRM6 Antibody.