HDAC10 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Histone deacetylase 10, HD10, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q969S8 | Иммуноген | Synthesized peptide derived from human HDAC10. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | Примечание | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.<br/><br/>Jenny J. Tong, Nucleic Acids Res., Mar 2002, 30: 1114 - 1123.<br/>Hung-Ying Kao, J. Biol. Chem., Jan 2002, 277: 187 - 193.<br/>Denise D. Fischer, J. Biol. Chem., Feb 2002, 277: 6656 - 6666.<br/>Matthew H. Brush, J. Biol. Chem., Feb 2004, 279: 7685 - 7691.<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Epigenetics and Nuclear Signaling,Stem cells | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using HDAC10 antibody.
| Western blot analysis of extracts from COS7 cells, using HDAC10 antibody.
| Western blot analysis of extracts from JK cells (Lane 2) and cos-7 cells (Lane 3), using HDAC10 antiobdy. The lane on the left is treated with synthesized peptide.
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