HIF1AN Antibody, HRP conjugatedСпецификацияОбъем | 50 мкг | Синонимы | Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Factor inhibiting HIF-1) (FIH-1) (Hypoxia-inducible factor asparagine hydroxylase), HIF1AN, FIH1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9NWT6 | Иммуноген | Recombinant Human Hypoxia-inducible factor 1-alpha inhibitor protein (2-254AA) | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA | Примечание | Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins. Also hydroxylates Asp and His residues within ARDs of ANK1 and TNKS2, respectively. Negatively regulates NOTCH1 activity, accelerating myogenic differentiation. Positively regulates ASB4 activity, promoting vascular differentiation. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | HRP | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Области исследований | Epigenetics and Nuclear Signaling, Cancer, Cardiovascular | Ссылка на страницу на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 50 мкг | Кат. номер: | CSB-PA865160LB01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: HIF1AN Antibody, HRP conjugated. Примечание: дополнительная информация (на английском языке). |
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