HK1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Hexokinase-1, EC 2.7.1.1, Hexokinase type I, HK I, Brain form hexokinase | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P19367 | | Иммуноген | Synthesized peptide derived from internal of human HXK1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.<br/><br/>Nishi S., Biochem. Biophys. Res. Commun. 157:937-943(1988).<br/>Ruzzo A., Biochem. J. 331:607-613(1998).<br/>Deloukas P., Nature 429:375-381(2004).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HeLa cells, using HXK1 antibody.
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Наименование: HK1 Antibody.