Объем | 50 мкг |
Синонимы | Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (HIP116) (RING finger protein 80) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3), HLTF, HIP116A RNF80 SMARCA3 SNF2L3 ZBU1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q14527 |
Иммуноген | Recombinant Human Helicase-like transcription factor protein (332-476AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA |
Примечание | Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity, This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Biotin |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Helicase-like transcription factor |
Области исследований | Epigenetics and Nuclear Signaling, Cancer, Cell biology |
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