HOMER1 AntibodyСпецификация| Объем | 100 мкг | | Синонимы | Homer protein homolog 1 (Homer-1), HOMER1, SYN47 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q86YM7 | | Иммуноген | Recombinant Human Homer protein homolog 1 protein (1-354AA) | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, IHC, Recommended dilution: IHC:1:20-1:200 | | Примечание | Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | Homer protein homolog 1 protein | | Области исследований | Neuroscience | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemistry of paraffin-embedded LO2 cells using CSB-PA03007A0Rb at dilution of 1:50
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Наименование: HOMER1 Antibody.