| Объем | 100 мкл |
| Синонимы | Insulin-like growth factor I receptor, CD221, IGF1R, kinase IGF1R, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P08069 |
| Иммуноген | Peptide sequence around aa.1159~1163 (D-I-Y-E-T) derived from Human IGF-1R . |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC, IF,WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200 |
| Примечание | This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.<br/><br/>Li S, et al. (1994) J Biol Chem, 269(51). <br/>Hernandez-Sanchez C, et al. (1995) J Biol Chem. <br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| Области исследований | Cancer,Developmental biology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells using IGF-1R(Ab-1161) Antibody and the same antibody preincubated with blocking peptide.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IGF-1R(Ab-1161) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Immunofluorescence staining of methanol-fixed MCF cells using IGF-1R(Ab-1161) Antibody.
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Наименование: IGF1R (Ab-1161) Antibody.