| Объем | 50 мкг |
| Синонимы | Inhibitor of growth protein 3 (p47ING3), ING3 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9NXR8 |
| Иммуноген | Recombinant Human Inhibitor of growth protein 3 protein (51-223AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:2000-1:10000, IHC:1:20-1:200 |
| Примечание | Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Inhibitor of growth protein 3 |
| Области исследований | Epigenetics and Nuclear Signaling, Cancer |
| Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: Hela whole cell lysate, Mouse brain tissue
All lanes: DACH1 antibody at 2.8µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 47, 12 kDa
Observed band size: 79 kDa
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Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA865171LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA865171LA01HU at dilution of 1:100
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Наименование: ING3 Antibody.