ITGA4 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | IA4, MGC90518, ITGA4 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P13612 | Иммуноген | Peptide sequence around aa.1024~1028(Y-I-N-S-K) derived from Human LPAM-1(Integrin a4, CD49d). | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA, WB,WB:1:500-1:1000 | Примечание | Integrins a-4/beta-1 (VLA-4) and a-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin a-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin a-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.<br/><br/>Iida J., Meijne A.M.L., Oegema T.R. Jr. J. Biol. Chem. 273:5955-5962(1998) <br/>Liu S., Thomas S.M., Woodside D.G., Rose D.M. Nature 402:676-681(1999) | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Области исследований | Cardiovascular,Immunology,Signal transduction,Stem cells | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extract from JK and Raji cells using LPAM-1(Integrin a4, CD49d) Antibody
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