ITGB3 (Ab-785) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CD61 antigen, GP3A, GPIIIa, ITB3, Platelet membrane glycoprotein IIIa | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P05106 | | Иммуноген | Peptide sequence around aa.783~787 (I-T-Y-R-G) derived from Human Integrin B3/ITGB3. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | <p>The Itg-Beta3 gene encodes the beta subunit of the platelet membrane adhesive protein receptor complex Itg-Beta3 protein, which belongs to the Integrin class of cell adhesion molecule receptors that share a common heterotrimeric structure with a and Beta subunits. It is a common Beta subunit of the platelet complex and of two other Integrins (Fibronectin and Vitronectin Receptors), which have distinct a subunits. Itg-Beta3 has been implicated in a wide variety of functions, including platelet aggregation and thrombosis and implantation, placentation, angiogenesis, bone remodeling, and tumor progression. Glanzmann Thrombasthenia can result from defects in the genes for either the Itg-a2B or the Itg-Beta3 subunit <br /><br />Sujoy Bhattacharya, et al. (2006) Biochem J. August 1, 397(Pt 3): 437</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Cardiovascular,Immunology,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HL60 and HT29 cells using Integrin b3(Ab-785) Antibody.
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Наименование: ITGB3 (Ab-785) Antibody.