JUN (Ab-63) AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Activator protein 1, AH119, AP-1, AP1, c-Jun | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P05412 | Иммуноген | Synthesized non-phosphopeptide derived from human c-Jun around the phosphorylation site of Serine 63. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,WB:1:500-1:3000 | Примечание | Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.<br/><br/>Wei W, et al. (2005). Cancer Cell. 8(1): 25-33.<br/>Sevilla A, et al. (2004). Oncogene.23(55): 8950-8958.<br/>Li L, et al. (2004). J Biol Chem.279(6): 4058-4065.<br/>Hurd C, et al. (2002). Oncogene.21(14): 2154-2160.<br/><br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Immunology,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from 293 cells, using c-Jun (Ab-63) antibody.
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