KAT5 Antibody, HRP conjugatedСпецификацияОбъем | 100 мкг | Синонимы | Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (Lysine acetyltransferase 5) (cPLA(2)-interacting protein), KAT5, HTATIP TIP60 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q92993 | Иммуноген | Recombinant Human Histone acetyltransferase KAT5 protein (3-512AA) | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA | Примечание | Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | HRP | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Области исследований | Epigenetics and Nuclear Signaling, Immunology, Microbiology | Ссылка на страницу на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 100 мкг | Кат. номер: | CSB-PA17849B0Rb | Цена (с НДС 20%): | по запросу | В корзину | Наименование: KAT5 Antibody, HRP conjugated. Примечание: дополнительная информация (на английском языке). |
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