Объем | 50 мкг |
Синонимы | Protease LasA (EC 3.4.24.-) (Staphylolytic protease), lasA |
Клональность | Polyclonal Antibody |
Организм | Pseudomonas aeruginosa |
uniprot | P14789 |
Иммуноген | Recombinant Pseudomonas aeruginosa Protease LasA protein (237-418AA) |
Источник | Rabbit |
Видовая специфичность | Pseudomonas aeruginosa |
Применение | ELISA |
Примечание | Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly-Gly-|-X substrates where X is Ala or Gly (PubMed:11179971). Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases (PubMed:2110137). Degradation of host elastin is likely to contribute to the pathogenicity of P.aeruginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in a given catalytic cycle, with the other stabilizing the catalytic intermediate (PubMed:20026068). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Области исследований | Others |
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