MAEA AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Macrophage erythroblast attacher, Erythroblast macrophage protein, Cell proliferation-inducing gene 5 protein, Lung cancer-related protein 10, HLC-10 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q7L5Y9 | Иммуноген | Synthesized peptide derived from internal of human MAEA. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,WB:1:500-1:3000 | Примечание | Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages, This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.<br/><br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>Hanspal M., Blood 92:2940-2950(1998).<br/>Bala S., Biochem. Biophys. Res. Commun. 342:1040-1048(2006). | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Immunology,Stem cells | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from COLO205 cells, using MAEA antibody.
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