| Объем | 100 мкл |
| Синонимы | C-TAK1, Cdc25C- associated protein kinase 1, EC 2.7.11.1, MAP/microtubule affinity-regulating kinase 3, Protein kinase STK10 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P27448 |
| Иммуноген | Synthesized peptide derived from N-terminal of human MARK3. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.<br/><br/>Peng C.Y., Cell Growth Differ. 9:197-208(1998).<br/>Sun T.-Q., Nat. Cell Biol. 3:628-636(2001).<br/>Wissing J., Mol. Cell. Proteomics 6:537-547(2007) |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HeLa cells and 293 cells, using MARK3 antibody.
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Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using MARK3 antibody.
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Наименование: MARK3 Antibody.