Объем | 100 мкл |
Синонимы | Mannose-binding protein C, MBP-C, MBP1, Mannan-binding protein, Mannose-binding lectin |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P11226 |
Иммуноген | Synthesized peptide derived from internal of human MBL2. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.<br/><br/>Ezekowitz R.A.B., J. Exp. Med. 167:1034-1046(1988).<br/>Sastry K., J. Exp. Med. 170:1175-1189(1989).<br/>Taylor M.E., Biochem. J. 262:763-771(1989).<br/> <br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Immunology |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells and 293 cells, using MBL2 antibody.
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