| Объем | 100 мкл |
| Синонимы | MDM2 oncogene, E3 ubiquitin protein ligase |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q00987 |
| Иммуноген | Synthetic peptide of human MDM2 |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| Примечание | This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane 1-2: Jurkat cells, 231 cells, Primary antibody: CSB-PA973311(MDM2 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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Наименование: MDM2 Antibody.