MMP2 AntibodyСпецификацияОбъем | 50 мкл | Синонимы | matrix metallopeptidase 2 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P08253 | Иммуноген | Synthetic peptide of human MMP2 | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,ELISA:1:1000-1:5000, WB:1:500-1:1000 | Примечание | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Cancer,Cardiovascular,Cell biology,Metabolism | Ссылка на страницу на сайте производителя | ссылка | Gel: 10%SDS-PAGE, Lysate: 40 ?g, Lane: Mouse liver tissue, Primary antibody: CSB-PA139729(MMP2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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