MNAT1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | AMS1, AdoMet synthetase, EC 2.5.1.6, MAT-I/III, MATA1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P51948 | Иммуноген | Synthesized peptide derived from internal of human MAT1. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,WB:1:500-1:3000 | Примечание | Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.<br/><br/>Tassan J.-P., EMBO J. 14:5608-5617(1995).<br/>Yee A., Cancer Res. 55:6058-6062(1995).<br/>Tirode F., Mol. Cell 3:87-95(1999). | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Epigenetics and Nuclear Signaling,Cell biology | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HeLa cells, HepG2 cells and 293 cells, using MAT1 antibody.
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