Объем | 100 мкл |
Синонимы | CRS2, FPP, Homeobox protein Hox-8, Homeobox protein MSX-2, HOX8 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P35548 |
Иммуноген | Synthesized peptide derived from Internal of human MSX2. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter.<br/><br/>Hodgkinson J.E., Biochim. Biophys. Acta 1174:11-16(1993).<br/>Jabs E.W., Cell 75:443-450(1993).<br/>Iimura T., DNA Seq. 8:87-92(1997).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cancer,Cardiovascular,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COLO205 cells, using MSX2 antibody.
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