NACC1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | BEND8, NACC1, NAC-1, BTBD14B, FLJ37383 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q96RE7 | | Иммуноген | Peptide sequence around aa.519~523(A-G-P-S-A) derived from Human NAC1 | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | <p>Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines. ",A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival.", <br />Nakayama K., Nakayama N., Davidson B.,et al. <br />Proc. Natl. Acad. Sci. U.S.A. 103:18739-18744(2006) ",NAC-1 controls cell growth and survival by repressing transcription of Gadd45GIP1, a candidate tumor suppressor.", <br />Nakayama K., Nakayama N., Wang T.-L., Shih I.-M. Cancer Res. 67:8058-8064(2007)</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Epigenetics and Nuclear Signaling,Developmental biology,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Rat and Mouse brain tissue using NAC1 Antibody.
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Наименование: NACC1 Antibody.