DTX1 Antibody, Biotin conjugated

Спецификация

Объем	50 мкг
Синонимы	E3 ubiquitin-protein ligase DTX1 (EC 2.3.2.27) (Protein deltex-1) (Deltex1) (hDTX1) (RING-type E3 ubiquitin transferase DTX1), DTX1
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q86Y01
Иммуноген	Recombinant Human E3 ubiquitin-protein ligase DTX1 protein (261-410AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	E3 ubiquitin-protein ligase DTX1
Области исследований	Epigenetics and Nuclear Signaling, Neuroscience, Cell biology
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	50 мкг
	Кат. номер:	CSB-PA773055LD01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: DTX1 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).