| Объем | 100 мкл |
| Синонимы | E2F transcription factor 2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q14209 |
| Иммуноген | Fusion protein of human E2F2 |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,ELISA:1:2000-1:5000, WB:1:500-1:2000 |
| Примечание | The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Gel: 12+15%SDS-PAGE, Lysate: 40 ?g, Lane: A549 cells, Primary antibody: CSB-PA103911(E2F2 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
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Наименование: E2F2 Antibody.