| Объем | 50 мкг |
| Синонимы | Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) (eIF4E-binding protein 1) (Phosphorylated heat- and acid-stable protein regulated by insulin 1) (PHAS-I), EIF4EBP1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q13541 |
| Иммуноген | Recombinant Human Eukaryotic translation initiation factor 4E-binding protein 1 protein (2-111AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, IHC, IF, Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 |
| Примечание | Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Eukaryotic translation initiation factor 4E-binding protein 1 |
| Области исследований | Epigenetics and Nuclear Signaling, Metabolism |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA623815LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA623815LA01HU at dilution of 1:100
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Immunofluorescent analysis of Hela cells using CSB-PA623815LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Наименование: EIF4EBP1 Antibody.