Объем | 100 мкл |
Синонимы | ELK1, ETS-domain protein Elk-1, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P19419 |
Иммуноген | Peptide sequence around aa.387~391 (P-R-S-P-A) derived from Human Elk1. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC, IF,WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200 |
Примечание | Elk-1 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene<br/><br/>Janknecht R, et al. (1993) EMBO J. 12(13): 5097-5104.<br/>Marais R, et al. (1993) Cell 73:381-393.<br/>Kortenjann M, et al. (1994) Mol Cell Biol. 14:4815-4824.<br/>Hill C S, et al. (1995) Cell. 80:199-211.<br/>Cavigelli M, et al. (1995) EMBO J. 14:5957-5964.<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Области исследований | Epigenetics and Nuclear Signaling,Cancer,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 and HT29 cells using Elk1(Ab-389) Antibody.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Elk1(Ab-389) Antibody
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Immunofluorescence staining of methanol-fixed Hela cells using Elk1(Ab-389) Antibody.
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