| Объем | 50 мкг |
| Синонимы | Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (hIRE1p) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1), Endoribonuclease (EC 3.1.26.-)], ERN1, IRE1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O75460 |
| Иммуноген | Recombinant Human Serine/threonine-protein kinase/endoribonuclease IRE1 protein (493-561AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA |
| Примечание | Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Biotin |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Serine/threonine-protein kinase/endoribonuclease IRE1 |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: ERN1 Antibody, Biotin conjugated.