Объем | 100 мкл |
Синонимы | estrogen receptor 2 (ER beta) |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q92731 |
Иммуноген | Fusion protein of human ESR2 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
Примечание | This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cancer,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA135769(ESR2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA135769(ESR2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ?200)
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Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane: Mouse brain tissue, Primary antibody: CSB-PA135769(ESR2 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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