| Объем | 100 мкл |
| Синонимы | FERM, RhoGEF and pleckstrin domain protein 2, FGD1-related Cdc42-GEF, FIR, FRG |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O94887 |
| Иммуноген | Synthesized peptide derived from Internal of human FIR. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion By similarity.<br/><br/>Nagase T., DNA Res. 5:31-39(1998).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/>Jandrig B., Oncogene 23:9295-9302(2004).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Neuroscience,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HuvEc cells, using FIR antibody.
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Наименование: FARP2 Antibody.