Объем | 100 мкл |
Синонимы | Fibroblast growth factor 23, FGF-23, Tumor-derived hypophosphatemia-inducing factor, HYPF, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9GZV9 |
Иммуноген | Synthesized peptide derived from internal of human FGF23. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 |
Примечание | Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL By similarity. Acts directly on the parathyroid to decrease PTH secretion By similarity. Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.<br/><br/>Yamashita T., Biochem. Biophys. Res. Commun. 277:494-498(2000).<br/>White K.E., Nat. Genet. 26:345-348(2000).<br/>Shimada T., Proc. Natl. Acad. Sci. U.S.A. 98:6500-6505(2001). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cancer,Developmental biology,Signal transduction,Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from JK cells, using FGF23 antiobdy.
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Immunofluorescence analysis of HuvEc cells, using FGF23 antibody.
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