Объем | 50 мкл |
Синонимы | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q96PU5 |
Иммуноген | Fusion protein of human NEDD4L |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Примечание | This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Epigenetics and Nuclear Signaling,Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA978449(NEDD4L Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ?200)
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