| Объем | 100 мкл |
| Синонимы | Nuclear factor interleukin-3-regulated protein, E4 promoter binding-protein 4, Interleukin-3 promoter transcriptional activator, Transcriptional activator NF-IL3A, Interleukin-3 binding-protein 1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q16649 |
| Иммуноген | Synthesized peptide derived from internal of human NFIL3. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts By similarity. Represses transcriptional activity of PER1 By similarity. Represses transcriptional activity of PER2 via the B-site on the promoter By similarity. Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) By similarity. Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock By similarity. Protects pro-B cells from programmed cell death By similarity.<br/><br/>Cowell I.G., Mol. Cell. Biol. 12:3070-3077(1992).<br/>Zhang W., Mol. Cell. Biol. 15:6055-6063(1995).<br/>Humphray S.J., Nature 429:369-374(2004).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Immunology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells and K562 cells, using NFIL3 antibody.
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Наименование: NFIL3 Antibody.