| Объем | 100 мкл |
| Синонимы | Nuclear factor interleukin-3-regulated protein (E4 promoter-binding protein 4) (Interleukin-3 promoter transcriptional activator) (Interleukin-3-binding protein 1) (Transcriptional activator NF-IL3A), NFIL3, E4BP4 IL3BP1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q16649 |
| Иммуноген | Recombinant Human Nuclear factor interleukin-3-regulated protein (133-462AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
| Примечание | Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts (By similarity). Represses transcriptional activity of PER1 (By similarity). Represses transcriptional activity of PER2 via the B-site on the promoter (By similarity). Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) (By similarity). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock (By similarity). Protects pro-B cells from programmed cell death (By similarity). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Абревеатура | Nuclear factor interleukin-3-regulated protein |
| Области исследований | Epigenetics and Nuclear Signaling, Immunology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: NFIL3antibody at 2.79µg/ml
Lane 1: HepG2 whole cell lysate
Lane 2: 293T whole cell lysate
Lane 3: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 51 kDa
Observed band size: 51, 90 kDa
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Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA621967ESR1HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA621967ESR1HU at dilution of 1:100
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Наименование: NFIL3 Antibody.