NGFR AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Gp80-LNGFR, NGF receptor, TNFRSF16, TNR16, low affinity neurotrophin receptor p75NTR | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P08138 | | Иммуноген | Synthesized peptide derived from internal of human TNR16. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 | | Примечание | Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake By similarity. Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.<br/><br/>Ye X., J. Biol. Chem. 274:30202-30208(1999).<br/>Wooten M.W., J. Biol. Chem. 276:7709-7712(2001).<br/>Bai D., Biochem. Biophys. Res. Commun. 309:552-557(2003). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HepG2 cells, using TNR16 antibody.
 | Immunofluorescence analysis of A549 cells, using TNR16 antibody.
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Наименование: NGFR Antibody.