NRAS AntibodyСпецификацияОбъем | 100 мкл | Синонимы | neuroblastoma RAS viral (v-ras) oncogene homolog | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P01111 | Иммуноген | Synthetic peptide of human NRAS | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 | Примечание | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA981790(NRAS Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ?200)
| Gel: 10%SDS-PAGE, Lysate: 40 ?g, Lane 1-2: Human fetal brain tissue, Jurkat cells, Primary antibody: CSB-PA981790(NRAS Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
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