Объем | 50 мкг |
Синонимы | Non-structural protein 1 (NS1) (NS1A), NS |
Клональность | Polyclonal Antibody |
Организм | Influenza A virus |
uniprot | P03495 |
Иммуноген | Recombinant Influenza A virus Non-structural protein 1 protein (152-237AA) |
Источник | Rabbit |
Видовая специфичность | Influenza A virus |
Применение | ELISA |
Примечание | Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1. In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm. Cellular protein synthesis is thereby shut off very early after virus infection. Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Non-structural protein 1 |
Ссылка на страницу на сайте производителя | ссылка |
| |