Объем | 50 мкг |
Синонимы | PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80), PHF21A, BHC80 KIAA1696 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q96BD5 |
Иммуноген | Recombinant Human PHD finger protein 21A protein (312-487AA) |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC, IF, Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Примечание | Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | PHD finger protein 21A |
Области исследований | Epigenetics and Nuclear Signaling, Neuroscience |
Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: Mouse liver tissue, Mouse kidney tissue
All lanes: PHF21A antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 75, 71 kDa
Observed band size: 75 kDa
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Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA017911LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA017911LA01HU at dilution of 1:100
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Immunofluorescent analysis of Hela cells using CSB-PA017911LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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