Phospho-DNM1L (Ser637) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | DLP1, DNM1L, DRP1, DVLP, Dymple | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | O00429 | | Иммуноген | Peptide sequence around phosphorylation site of Serine637(K-L-S(p)-A-R) derived from Human DRP1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | <p>Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. <br /><br />Shin H.-W., J. Biochem. 122:525-530(1997).<br />Hong Y.-R., Biochem. Biophys. Res. Commun. 249:697-703(1998).<br />Imoto M., J. Cell Sci. 111:1341-1349(1998).</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Ser637 | | Области исследований | Neuroscience,Cancer,Cell biology,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from JK cells and K562 cells using DRP1 (Phospho-Ser637) Antibody.The lane on the right is treated with the antigen-specific peptide.
 | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA297783 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Phospho-DNM1L (Ser637) Antibody.
Примечание: дополнительная информация (на английском языке). |
|
