Phospho-EGFR (Tyr869) Antibody

Спецификация

Объем	100 мкл
Синонимы	ERBB1, Receptor protein-tyrosine kinase ErbB-1, kinase EGFR
Клональность	Polyclonal Antibody
Организм	Human
uniprot	P00533
Иммуноген	Peptide sequence around phosphorylation site of tyrosine 869 (K-E-Y(p)-H-A) derived from Human EGFR.
Источник	Rabbit
Видовая специфичность	Human, Mouse, Rat
Применение	ELISA, WB,WB:1:500-1:1000
Примечание	Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin. <br/><br/>Inoue A, et al. (2005) PLoS Med, 2(1): e13<br/>Sun H, et al. (2004) EMBO J, 23(1): 100-110<br/>Kanner SB, et al. (1991) Mol Cell Biol, 11(2): 713-720<br/>Wu TT, et al. (1998) Mol Biol Cell, 9(7): 1661-1674<br/>O
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Non-conjugated
Буффер	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Форма	liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Абревеатура	Phospho-Tyr869
Области исследований	Cancer,Signal transduction
Ссылка на страницу на сайте производителя	ссылка
Western blot analysis of extracts from MDA cells untreated or treated with EGF using EGFR(Phospho-Tyr869) Antibody.

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкл
	Кат. номер:	CSB-PA184845
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Phospho-EGFR (Tyr869) Antibody. Примечание: дополнительная информация (на английском языке).