Phospho-EIF2AK2 (Thr451) Antibody

Спецификация

Объем	100 мкл
Синонимы	ADRB2, E2AK2, EIF2AK2, EIF2aK, PRKR
Клональность	Polyclonal Antibody
Организм	Human
uniprot	P19525
Иммуноген	Peptide sequence around phosphorylation site of threonine 451 (K-G-T(p)-L-R) derived from Human PKR.
Источник	Rabbit
Видовая специфичность	Human, Mouse
Применение	ELISA, IHC,IHC:1:50-1:100
Примечание	<p>Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection. <br /><br />Ingrid K. Ruf, et,al. (2005) J. Virol , 79: 14562 - 14569. <br />Christy M. Hebner,et,al. (2006) J. Gen. Virol , 87: 3183 - 3193. <br />Rika van Huizen, et,al. (2003) J. Biol. Chem , 278: 15558 - 15564. <br /></p>
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Non-conjugated
Буффер	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Форма	liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Абревеатура	Phospho-Thr451
Области исследований	Signal transduction
Ссылка на страницу на сайте производителя	ссылка
Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using PKR(Phospho-Thr451) Antibody(left) or the same antibody preincubated with blocking peptide(right).

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкл
	Кат. номер:	CSB-PA035578
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Phospho-EIF2AK2 (Thr451) Antibody. Примечание: дополнительная информация (на английском языке).