| Объем | 100 мкл |
| Синонимы | ER, ESR, ESR1, ESTR, ESTRA |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P03372 |
| Иммуноген | Peptide sequence around phosphorylation site of serine106 (S-P- S(p)-P-L) derived from Human Estrogen Receptor-a. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, IF,WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200 |
| Примечание | Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.<br/><br/>Marone R, et al. (2004) Nat Cell Biol, 6(6): 515-22.<br/>Ren Z, et al. (2002) J Biol Chem, 277(41): 38486-93.<br/>Ouyang X,et al. (1998)Carcinogenesis, 19(11): 2013-9.<br/>Ouyang X,et al. (1998) Exp Cell Res, 241(2): 467-75.<br/>Klapper, L. N. et al. (2000) Cancer Res. 60, 3384-3388.<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser106 |
| Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cancer,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from MCF7 cells untreated or treated with EGF using Estrogen Receptor-a(Phospho-Ser106) Antibody.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Estrogen Receptor-a(Phospho-Ser106) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Immunofluorescence staining of methanol-fixed MCF cells using Estrogen Receptor-a(Phospho-Ser106) Antibody.
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Наименование: Phospho-ESR1 (Ser106) Antibody.